By Abul K. Abbas MBBS, Andrew H. H. Lichtman MD PhD, Shiv Pillai MBBS PhD

Understand the entire crucial options in immunology with Basic Immunology: services and problems of the Immune System! This concise, targeted textual content provide you with an up-to-date, available advent to the workings of the human immune approach.

  • Efficiently grasp the immunology info you would like through clinically targeted content material, logically prepared through mechanism.
  • Apply what you will have discovered to real-world occasions by referencing the appendix of medical circumstances.
  • Enhance your learning with the aid of various full-color illustrations and worthy tables, in addition to precis bins, assessment questions, and a word list of immunology terms.
  • Study immunology anywhere! on-line entry to www.StudentConsult.com opens the door to an more advantageous booklet and ancillary components!

  • Visualize advanced immunology techniques with a totally up to date paintings program.
  • Test your knowledge. New PowerPoint assessment slides extra to www.StudentConsult.com are perfect for examine sessions.

Show description

Read or Download Basic Immunology: Functions and Disorders of the Immune System, 4e PDF

Best infectious diseases books

Infectious Disease Management in Animal Shelters

"Infectious illness administration in Animal Shelters" is a complete consultant to combating, handling, and treating disorder outbreaks in shelters. Emphasizing ideas for the prevention of disease and mitigation of sickness, this e-book presents special, sensible information about basic ideas of sickness keep watch over and particular administration of vital illnesses affecting canines and cats in crew residing environments.

G-CSF Receptor

The G-CSF receptor is a sort I membrane protein which belongs to the cytokine receptor superfamily, and is in particular expressed in mature neutrophils and neutrophilic precursors. Binding of G-CSF to G-CSFR induces its dimerization. The dimerized receptor transduces progress and differentiation signs that are mediated by way of the N-terminal and C-terminal halves of the G-CSFR cytoplasmic zone.

Avian Immunology

The technology underpinning avian immunology is essential to realizing uncomplicated immunological rules and the outstanding good points of the avian immune process, as varied thoughts birds have followed promises very important evolutionary insights. This ebook offers the main whole photograph of the avian immune process thus far.

Molecular Immunology

Immune responses consequence from the activation of an problematic community of interacting cells taking place in particular microenvironments. consciousness in recent times has been focussed intensively on a couple of matters. integrated between those are: the developmental pathways of the 2 significant varieties of lymphocytes, T and B cells; the character in their particular receptors for antigen and in their a number of accent floor molecules; the next destiny of the cells following stumble upon with antigen provided as such or on various cells; and the functionality of the effector molecules produced after profitable activation by means of antigen.

Extra resources for Basic Immunology: Functions and Disorders of the Immune System, 4e

Sample text

By sensing microbes and interacting with lymphocytes, especially T cells, dendritic cells constitute an important bridge between innate and adaptive immunity. We discuss the properties and functions of these cells further in Chapter 3, in the context of antigen display, which is a major function of dendritic cells. Mast Cells Mast cells are bone marrow–derived cells with abundant cytoplasmic granules that are present in the skin and mucosal epithelium. Mast cells can be activated by microbial products binding to TLRs, as part of innate immunity, or by a special antibody-dependent mechanism.

Although our emphasis thus far has been on cellular receptors, the innate immune system also contains several circulating molecules that recognize and provide defense against microbes, as discussed later. COMPONENTS OF INNATE IMMUNITY The components of the innate immune system include epithelial cells, sentinel cells in tissues (macrophages, dendritic cells, and others), NK cells, and a number of plasma proteins. We next discuss the properties of these cells and soluble proteins and their roles in innate immune responses.

2–7, B). They also ingest microbes in the blood and in tissues. Monocytes that enter extravascular tissues differentiate into cells called macÂ�rophages, which, unlike neutrophils, survive in these sites for long periods. Blood monocytes and tissue macrophages are two stages of the same cell lineage, which often is called the mononuclear phagocyte system (Fig. 2–8). ) Resident macrophages are found in healthy connective tissue and all organs in the body. Macrophages serve several important roles in host defense—they produce cytokines that initiate and regulate inflammation, they ingest and destroy microbes, and they clear dead tissues and initiate the process of tissue repair (Fig.

Download PDF sample

Rated 4.78 of 5 – based on 15 votes